Artificially constructed from the same organic phospholipids that make up cells and biomembranes, liposomes are a drug delivery alternative for both hydrophilic and hydrophobic drugs. Fujifilm formulates liposomes harnessing nano-dispersion technologies developed over 80 years of photo-film manufacturing.
Liposomes provide a delivery system that carries the required amount of a drug to the specific area of the body. Because of that, one potential application for liposomes is anti-cancer formulations. Studies have suggested that liposomes are delivered to tumors through the enhanced permeability and retention (EPR) effect1. As a passive targeting mechanism, EPR allows the accumulation of drugs within the tumor tissue thanks to immature, highly permeable vasculature and ineffective lymphatic system that allow efficient extravasation of such macromolecules.
1 Yingchoncharoen P., Kalinowski D.S., Richardson D.R. 2016. Lipid-Based Drug Delivery Systems in Cancer Therapy: What Is Available and What Is Yet to Come. Pharmacol Rev. 68(3):701-87.
- Lipid synthesis: synthesis and optimization of generic and original lipids.
- Logical optimization: application of molecular dynamics analysis for liposomal shell formulation tailored to specific payloads.
- Manufacturing: stable production of liposomes of homogeneous shape and uniform size.
We believe in the power of collaboration
We are seeking the following partners:
② Companies seeking process development and/or analytical development services for existing liposome formulations
③ Companies in need of GMP manufacturing capabilities for liposome drug products
Access our Resources page for technical information on our services.
This webpage is solely intended to provide information to companies or individuals seeking partnering opportunities in connection with Fujifilm’s Contract Services.